Article
A common thrombomodulin amino acid dimorphism is associated with myocardial infarction.
Thrombosis and haemostasis - 1 Feb 1997
Norlund L, Holm J, Zöller B, Ohlin A K
Abstract excerpt
Endothelial dysfunction and haemostatic imbalance are believed to be important aetiological factors in the development of acute coronary syndromes. Thrombomodulin (TM) is an integral membrane protein crucial for normal endothelial function and activation of the protein C anticoagulant pathway. We have investigated the importance of a common C/T dimorphism in the TM gene (nucleotide 1418) for development of...
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