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Article

Regulation of surface localization of the small conductance Ca2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase.

The Journal of biological chemistry - 28 Apr 2006

Ren Yajun, Barnwell Lyndon F, Alexander Jon C, Lubin Farah D, Adelman John P, Pfaffinger Paul J, Schrader Laura A, Anderson Anne E

Abstract excerpt

Small conductance, Ca2+-activated voltage-independent potassium channels (SK channels) are widely expressed in diverse tissues; however, little is known about the molecular regulation of SK channel subunits. Direct alteration of ion channel subunits by kinases is a candidate mechanism for functional modulation of these channels. We find that activation of cyclic AMP-dependent protein kinase (PKA) with forskolin...

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PMID: 16513649
DOI: 10.1074/jbc.M513125200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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