Article
Characterization of drug resistance genes in Indian Plasmodium falciparum and Plasmodium vivax field isolates.
Acta tropica - 1 Jul 2024
Narang Geetika, Jakhan Jahnvi, Tamang Suman, Yadav Karmveer, Singh Vineeta
Abstract excerpt
One of the major challenges for malaria control and elimination is the spread and emergence of antimalarial drug resistance. Mutations in Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) field isolates for five drug resistance genes viz. crt, mdr1, dhps, dhfr and kelch known to confer resistance to choloroquine (CQ), sulfadoxine-pyrimethamine (SP) and artemisinin (ART) and its derivatives were analyzed. A...
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