Article
Distribution pattern of amino acid mutations in chloroquine and antifolate drug resistance associated genes in complicated and uncomplicated Plasmodium vivax isolates from Chandigarh, North India.
BMC infectious diseases - 15 Sept 2020
Kaur Hargobinder, Sehgal Rakesh, Kumar Archit, Bharti Praveen K, Bansal Devendra, Mohapatra Pradyumna K, Mahanta Jagadish, Sultan Ali A
Abstract excerpt
BACKGROUND: The increasing antimalarial drug resistance is a significant hindrance to malaria control and elimination programs. For the last six decades, chloroquine (CQ) plus pyrimethamine remains the first-line treatment for P. vivax malaria. Regions where both P. falciparum and P. vivax co-exist, P. vivax is exposed to antifolate drugs due to either misdiagnosis or improper treatment that causes selective drug...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.