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Article

Aberrant stalk development and breakdown of tip dominance in Dictyostelium cell lines with RNAi-silenced expression of calcineurin B.

BMC developmental biology - 2 Mar 2006

Boeckeler Katrina, Tischendorf Gilbert, Mutzel Rupert, Weissenmayer Barbara

Abstract excerpt

BACKGROUND: Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, plays important roles in various cellular processes in lower and higher eukaryotes. Here we analyze the role of calcineurin in the development of Dictyostelium discoideum by RNAi-mediated manipulation of its expression. RESULTS: The cnbA gene of Dictyostelium discoideum which encodes the regulatory B subunit (CNB) of calcineurin was...

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Identifiers

PMID: 16512895
DOI: 10.1186/1471-213X-6-12
PMCID: PMC1431509

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Source receipt: pubmed, retrieved 7 Sept 2026.

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