Article
Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities.
The EMBO journal - 1 Sept 1991
Haber L T, Walker G C
Abstract excerpt
The Salmonella typhimurium and Escherichia coli MutS protein is one of several methyl-directed mismatch repair proteins that act together to correct replication errors. MutS is homologous to the Streptococcus pneumoniae HexA mismatch repair protein and to the Duc1 and Rep1 proteins of human and m...
Topics
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- Blotting, Western
- DNA Repair
- DNA, Fungal
- DNA-Binding Proteins
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli Proteins
- Genetic Complementation Test
- Humans
- Hydrolysis
- Mice
- Molecular Sequence Data
- MutS DNA Mismatch-Binding Protein
- Mutation