Article
The serotonin transporter promoter polymorphism and suicide.
Neuroscience letters - 29 May 2006
Helbecque Nicole, Sparks D Larry, Hunsaker John C, Amouyel Philippe
Abstract excerpt
Serotonergic dysfunction has been implicated in mood disorders and in the pathophysiology of suicidality. A functional polymorphism (a 44-base pair insertion (L)/deletion (S)) in the promoter of the gene encoding the serotonin transporter (5-HTTLPR), associated with mood disorders, has been inconsistently associated with suicidality. To add to this debate, we designed a case-control study involving 62 suicide...
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