Article
Possible association between serotonin transporter gene polymorphism and violent suicidal behavior in mood disorders.
Biological psychiatry - 15 Aug 2000
Bellivier F, Szöke A, Henry C, Lacoste J, Bottos C, Nosten-Bertrand M, Hardy P, Rouillon F, Launay J M, Laplanche J L, Leboyer M
Abstract excerpt
BACKGROUND: Genes involved in the serotonin system are major candidates in association studies of suicidal behavior. In this case-control study we investigated whether the serotonin transporter (5-HTT) gene encoding the protein responsible for the reuptake of serotonin from the synapse after its release from serotonergic neurons is a susceptibility factor for suicidal behavior. METHODS: A functional polymorphism...
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