Influence of the helper virus on expression of beta-galactosidase from a defective HSV-1 vector, pHSVlac.

doi:10.1016/0166-0934(91)90161-r

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Article

Influence of the helper virus on expression of beta-galactosidase from a defective HSV-1 vector, pHSVlac.

Journal of virological methods - 1 Jan 2000

Geller A I

Abstract excerpt

Defective herpes simplex virus type 1 (HSV-1) vectors can deliver genes into both mitotic and postmitotic cells, including neurons and these vectors, therefore, have great potential use. pHSVlac, the prototype HSV-1 vector, expresses the E. coli Lac Z gene from the HSV-1 immediate early 4/5 promo...

Topics

Adrenal Gland Neoplasms
Animals
DNA, Viral
Gene Expression Regulation, Viral
Genetic Vectors
Haplorhini
Helper Viruses
Mutation
Pheochromocytoma
Rats
Simplexvirus
Tumor Cells, Cultured
beta-Galactosidase

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