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Article

The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors.

15 Oct 1996

Abstract excerpt

Herpes simplex virus vectors are being developed for delivery and expression of human genes to the central nervous system, selective destruction of cancer cells, and as carriers for genes encoding antigens that induce protective immunity against infectious agents. Vectors constructed to meet these objectives must differ from wild-type virus with respect to host range, reactivation from latency, and expression of...

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PMID: 8876131
DOI: 10.1073/pnas.93.21.11307

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