Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CtBP2 contributes to malignant development of human esophageal squamous cell carcinoma by regulation of p16<sup>INK4A</sup>

18 Dec 2012

Abstract excerpt

C-terminal binding protein-2 (CtBP2), as a transcriptional co-repressor, has been shown to mediate the repression of p16(INK4A) , a tumor suppressor gene product, in primary human cells. Here we aimed to investigate how the correlation between CtBP2 and p16(INK4A) influenced the development of esophageal squamous cell carcinoma (ESCC). Immunohistochemistry of ESCC tissue sections indicated that the CtBP2 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Chronic Myeloid Leukemia Treatments
Share to Kruppel-like factors research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23255392
DOI: 10.1002/jcb.24475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CtBP2 contributes to malignant development of human esophageal squamous cell carcinoma by regulation of p16<sup>INK4A</sup>PMID 23255392Read ↗

p16 expression in Barrett's esophagus and esophageal adenocarcinoma: association with genetic and epigenetic alterationsSemantic proximity Read ↗

Multidimensional analysis of the role of BRI3BP in the occurrence, development and prognosis of esophageal cancerSemantic proximity Read ↗

CUL4B enhances the malignant phenotype of esophageal squamous cell carcinoma by suppressing TGFBR3 expression.Semantic proximity Read ↗

Molecular mechanism and clinical significance of Notch3 negative regulation of BRD4 on the growth and survival of esophageal squamous cell carcinomaSemantic proximity Read ↗

XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathwaySemantic proximity Read ↗

TRAIP enhances progression of tongue squamous cell carcinoma through EMT and Wnt/β-catenin signaling by interacting with DDX39ASemantic proximity Read ↗

p16 INK4a hypermethylation and p53, p16 and MDM2 protein expression in Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

Function of p21 and its therapeutic effects in esophageal cancer (Review)Semantic proximity Read ↗

FOXK1 regulates malignant progression and radiosensitivity through direct transcriptional activation of CDC25A and CDK4 in esophageal squamous cell carcinomaSemantic proximity Read ↗

The C-terminal of the E1A binding protein 2 enhances the metastatic potential of keratinocyte-derived cutaneous squamous carcinoma cells via the gp130/JAK2/Stat1 signaling pathwaySemantic proximity Read ↗

Id‐1 promotes proliferation of p53‐deficient esophageal cancer cellsSemantic proximity Read ↗

SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.