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Article

Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3.

Circulation - 1 Aug 1991

Seko Y, Shinkai Y, Kawasaki A, Yagita H, Okumura K, Takaku F, Yazaki Y

Abstract excerpt

BACKGROUND: Cell-mediated autoimmunity has been strongly implicated in the pathogenesis of viral myocarditis. METHODS AND RESULTS: Using a murine model of acute myocarditis caused by coxsackievirus B3, we analyzed the phenotypes and morphology of the infiltrating cells in the hearts by immunofluorescence and electron microscopy. We also examined the expression of a cytolytic factor, perforin, in the infiltrating...

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Identifiers

PMID: 1650300
DOI: 10.1161/01.cir.84.2.788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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