Article
Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin.
Carcinogenesis - 1 Aug 2006
Thirumaran Ranjit Kumar, Bermejo Justo Lorenzo, Rudnai Peter, Gurzau Eugene, Koppova Kvetoslava, Goessler Walter, Vahter Marie, Leonardi Giovanni S, Clemens Felicity, Fletcher Tony, Hemminki Kari, Kumar Rajiv
Abstract excerpt
In addition to environmental exposures like UV radiation and, in some cases, arsenic contamination of drinking water, genetic factors may also influence the individual susceptibility to basal cell carcinoma of skin (BCC). In the present study, 529 cases diagnosed with BCC and 533 controls from Hungary, Romania and Slovakia were genotyped for one polymorphism in each of seven DNA repair genes. The variant allele...
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