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Article

Role played by human mannose-binding lectin polymorphisms in pulmonary tuberculosis.

The Journal of infectious diseases - 1 Mar 2009

Capparelli Rosanna, Iannaccone Marco, Palumbo Daniela, Medaglia Chiara, Moscariello Emilio, Russo Alfredo, Iannelli Domenico

Abstract excerpt

BACKGROUND: Mannose-binding lectin (MBL) activates the complement system in an antibody-independent manner, enhances complement-mediated phagocytosis, and plays a major role in the regulation of inflammatory cytokine release by monocytes. METHODS: Case patients (277 patients with pulmonary tuberculosis) and control subjects (288 household contacts) were tested by polymerase chain reaction (PCR) for polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19199550
DOI: 10.1086/596658

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