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Article

A stochastic model of cancer initiation including a bystander effect.

Journal of theoretical biology - 21 Aug 2006

Østby Ivar, Øyehaug Leiv, Steen Harald B

Abstract excerpt

A stochastic model of cancer initiation is considered. The model is used to evaluate whether a bystander effect may be important in the pre-malignant and malignant stages of carcinogenesis, and furthermore, on the basis of epidemiological data, to estimate the mutation rates of genes involved in the development of oral leukoplakias. The bystander effect is defined here as the capability of oncogenic mutations to...

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Identifiers

PMID: 16499930
DOI: 10.1016/j.jtbi.2006.01.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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