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Article

HLA association is different in children and adults with severe acquired aplastic anemia.

Pediatric blood & cancer - 1 Feb 2007

Führer Monika, Durner Jürgen, Brünnler Günter, Götte Heiko, Deppner Cornelia, Bender-Götze Christine, Albert Ekkehard

Abstract excerpt

BACKGROUND: Severe aplastic anemia (SAA) is defined as pancytopenia caused by bone marrow failure. The pathogenesis of SAA is thought to involve autoimmune processes. Increased susceptibility to autoimmunity has been shown to be associated with several different HLA alleles. In SAA, few large studies based on data mainly from adults describe a positive HLA correlation with HLA-DR2 (DRB1*15) and HLA-B14....

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Source

Identifiers

PMID: 16496287
DOI: 10.1002/pbc.20785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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