Article
HLA alleles, haplotypes frequencies, and their association with hematological disorders: a report from 1550 families whose patients underwent allogeneic bone marrow transplantation in Egypt.
Immunogenetics - 1 Aug 2024
ElNahass Yasser, Mekky Nourhan, Abdelfattah Nabil M, Abdelfattah Raafat, Samra Mohamed, Fahmy Omar A, Fathy Gamal, Elmetnawy Wafaa, Sabet Salwa, Bassiouny Heba, Nader Heba, ElHaddad Alaa, Mahmoud H K
Abstract excerpt
HLA alleles are representative of ethnicities and may play important roles in predisposition to hematological disorders. We analyzed DNA samples for HLA-A, -B, -C, -DRB1, and -DQB1 loci, from 1550 patients and 4450 potential related donors by PCR-SSO (Polymerase chain reaction sequence-specific oligonucleotides) and estimated allele frequencies in donors and patients from 1550 families who underwent bone marrow...
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