Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ancestry of the HLA-DRB1*15 allele predisposes the Mexican mestizo to the development of aplastic anemia.

Human immunology - 1 Aug 2012

Fernández-Torres Javier, Flores-Jiménez Denhi, Arroyo-Pérez Antonio, Granados Julio, López-Reyes Alberto

Abstract excerpt

UNLABELLED: Aplastic anemia (AA) is a hematological disorder characterized by pancytopenia in peripheral blood and hypoplasia in the bone marrow; the majority of cases have no known etiology, but it is thought that genetic and environmental factors can be involved in its pathogenesis. From the genetic viewpoint, it has been reported a significant increase frequency of the human leukocyte antigen HLA-DRB1(∗)15 in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Aplastic
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Ethnicity

Share to Gene Frequency

Share to HLA-DRB1 Chains

Share to Infant

Share to Mexico

Source

Identifiers

PMID: 22580214
DOI: 10.1016/j.humimm.2012.04.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ancestry of the HLA-DRB1*15 allele predisposes the Mexican mestizo to the development of aplastic anemia.PMID 22580214Read ↗

Association of Human Leukocyte Antigen DRB1*15 and DRB1*15:01 Polymorphisms with Response to Immunosuppressive Therapy in Patients with Aplastic Anemia: A Meta-Analysis.Semantic proximity Read ↗

[Expression of HLA-DRB1*15 genotype in children with acquired aplastic anemia and its relation to effect of immunosuppressive therapy].Semantic proximity Read ↗

[Association of HLA DRB1 polymorphism with susceptibility to myelodysplastic syndrome and aplastic anemia in Chinese Han population].Semantic proximity Read ↗

Associations between the HLA-A/B/DRB1 polymorphisms and aplastic anemia: evidence from 17 case-control studies.Semantic proximity Read ↗

HLA alleles, haplotypes frequencies, and their association with hematological disorders: a report from 1550 families whose patients underwent allogeneic bone marrow transplantation in Egypt.Semantic proximity Read ↗

Association of HLA class II (-DRB1,-DQB1,-DPB1) alleles and haplotypes on susceptibility to aplastic anemia in northern Chinese Han.Semantic proximity Read ↗

Human leukocyte antigen-DRB1 gene polymorphism and aplastic anemia: A meta-analysis.Semantic proximity Read ↗

HLA association is different in children and adults with severe acquired aplastic anemia.Semantic proximity Read ↗

[Relationship between polymorphism of HLA-A, -B, -DRB1 alleles and susceptibility of children to acquired aplastic anemia].Semantic proximity Read ↗

The frequency of HLA class I and II alleles in Pakistani patients with aplastic anemia.Semantic proximity Read ↗

Correlations between HLA-A, HLA-B and HLA-DRB1 allele polymorphisms and childhood susceptibility to acquired aplastic anemia.Semantic proximity Read ↗

Molecular identification of the HLA-DRB1-DQB1 for diagnosis and follow-up of acute leukemias.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.