Article
Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.
Antimicrobial agents and chemotherapy - 1 Mar 1993
Wang Y, Huang W M, Taylor D E
Abstract excerpt
The gyrA gene of Campylobacter jejuni UA580, which encodes the A subunit of DNA gyrase, was cloned and its nucleotide sequence was determined. An open reading frame of 2,589 nucleotides was identified, which could code for a polypeptide of 863 amino acids with a M(r) of 97 kDa. Both the nucleotid...
Topics
- 4-Quinolones
- Amino Acid Sequence
- Anti-Infective Agents
- Base Sequence
- Campylobacter jejuni
- Chromosome Mapping
- Chromosomes, Bacterial
- Cloning, Molecular
- DNA Topoisomerases, Type II
- DNA, Bacterial
- Drug Resistance, Microbial
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Topoisomerase II Inhibitors