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Article

Complete deletion of the AZFb interval from the Y chromosome in an oligozoospermic man

17 Aug 2010

Abstract excerpt

BACKGROUND: Deletion of the entire AZFb interval from the Y chromosome is strictly associated with azoospermia arising from maturation arrest during meiosis. Here, we describe the exceptional case of an oligozoospermic man, 13-1217, with an AZFb + c (P5/distal-P1) deletion. Through the characterization of this patient, and two AZFb (P5/proximal-P1) patients with maturation arrest, we have explored three possible...

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PMID: 20716563
DOI: 10.1093/humrep/deq209

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