Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses.

doi:10.1016/0042-6822(91)90994-m

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses.

Virology - 1 Aug 1991

Yokomori K, Banner L R, Lai M M

Abstract excerpt

The hemagglutinin-esterase (HE) membrane glycoprotein is present only in some members of the coronavirus family, including some strains of mouse hepatitis virus (MHV). In the JHM strain of MHV, expression of the HE gene is variable and corresponds to the number of copies of a UCUAA pentanucleotide sequence present at the 3'-end of the leader RNA. This copy number varies among MHV strains, depending on their...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
DNA, Viral
Electrophoresis, Polyacrylamide Gel
Gene Expression
Glycoproteins
Hemagglutinins, Viral
Introns
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Murine hepatitis virus

Mutation

RNA, Messenger

RNA, Viral

Sequence Homology, Nucleic Acid

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1649505
DOI: 10.1016/0042-6822(91)90994-m
PMCID: PMC7130567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1649505-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses.PMID 1649505Read ↗

Both Spike and Background Genes Contribute to Murine Coronavirus NeurovirulenceSemantic proximity Read ↗

Expression of Hemagglutinin Esterase Protein from Recombinant Mouse Hepatitis Virus Enhances NeurovirulenceSemantic proximity Read ↗

Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains.Semantic proximity Read ↗

Coronavirus defective-interfering RNA as an expression vector: the generation of a pseudorecombinant mouse hepatitis virus expressing hemagglutinin-esterase.Semantic proximity Read ↗

Heterogeneity of subgenomic mRNAs of a mutant mouse hepatitis virus strain JHM2C.Semantic proximity Read ↗

Variability of persisting MHV RNA sequences constituting immune and replication-relevant domains.Semantic proximity Read ↗

Exceptional flexibility in the sequence requirements for coronavirus small envelope protein function.Semantic proximity Read ↗

Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA.Semantic proximity Read ↗

The Small Envelope Protein E Is Not Essential for Murine Coronavirus ReplicationSemantic proximity Read ↗

Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes.Semantic proximity Read ↗

A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor.Semantic proximity Read ↗

Inactivation of Expression of Gene 4 of Mouse Hepatitis Virus Strain JHM Does Not Affect Virulence in the Murine CNSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.