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Article

Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes.

Proceedings of the National Academy of Sciences of the United States of America - 2 Feb 1999

Dawid S, Barenkamp S J, St Geme J W

Abstract excerpt

Expression of a number of eukaryotic genes is regulated by long stretches of tandem repeats located within the 5' untranslated region of the particular gene. In this study, we describe a regulatory system in Haemophilus influenzae with striking similarities to those found in eukaryotes. We show that expression of the HMW1 and HMW2 adhesins varies based on the number of 7-bp tandem repeats in the hmw1A and hmw2A...

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Identifiers

PMID: 9927696
DOI: 10.1073/pnas.96.3.1077
PMCID: PMC15353

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