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Article

Evaluation of binding affinity of protein-mutant DNA complexes in solution by laser spray mass spectrometry.

Journal of the American Society for Mass Spectrometry - 1 Apr 2006

Shi Xiangguo, Nishimura Yoshifumi, Akashi Satoko, Takamizawa Atsushi, Hiraoka Kenzo

Abstract excerpt

We have applied laser spray mass spectrometry developed by Hiraoka et al. to investigate the binding affinity of protein-mutant DNA complexes. The results were compared with our previous data of collision-induced dissociation (CID) experiments using electrospray ionization mass spectrometry (ESI-MS). Systematic experiments were carried out on the complexes of the c-Myb DNA binding domain (c-Myb DBD) bound to...

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Identifiers

PMID: 16490360
DOI: 10.1016/j.jasms.2005.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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