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Article

Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2006

Yeh Shiou-Hwei, Wu Dai-Chen, Tsai Ching-Yi, Kuo Ti-Jung, Yu Wei-Che, Chang Yuan-Shau, Chen Chi-Ling, Chang Ching-Fang, Chen Ding-Shinn, Chen Pei-Jer

Abstract excerpt

PURPOSE: Allelic loss at chromosome 4q21-23 occurs frequently in human hepatocellular carcinoma, and the putative tumor suppressor gene (TSG) has not yet been identified. We studied the Fas-associated phosphatase-1 (FAP-1) gene as a potential candidate TSG in this region. EXPERIMENTAL DESIGN: The expression level of FAP-1 RNA in hepatocellular carcinomas was evaluated by RNase protection and quantitative PCR....

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Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 4

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Identifiers

PMID: 16489062
DOI: 10.1158/1078-0432.CCR-05-1383

Genes

FAP

Provenance

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