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Article

Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer.

Pancreas - 1 May 2008

Park Jong Y, Helm James F, Zheng Weipeng, Ly Quan P, Hodul Pamela J, Centeno Barbara A, Malafa Mokenge P

Abstract excerpt

OBJECTIVES: Few genetic mutations have been identified in pancreatic adenocarcinoma, whereas epigenetic changes that lead to gene silencing are known in several genes. Because SLC5A8 is regarded as a potential tumor suppressor gene that is down-regulated by epigenetic changes in several other cancers, we sought to characterize promoter methylation status and its relationship to SLC5A8 expression in pancreatic...

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PMID: 18437076
DOI: 10.1097/MPA.0b013e3181630ffe

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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