Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell Adhesion to Fibronectin (CAM-DR) Influences Acquired Mitoxantrone Resistance in U937 Cells

15 Feb 2006

Abstract excerpt

Cell adhesion to fibronectin is known to confer a temporally related cell adhesion-mediated drug resistance (CAM-DR). However, it is unknown whether cell adhesion during drug selection influences the more permanent form of acquired drug resistance. To examine this question, we compared the acquisition of mitoxantrone resistance in U937 cells adhered to fibronectin versus cells selected in a traditional suspension...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Drug Transport and Resistance Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16489039
DOI: 10.1158/0008-5472.can-05-3256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Cell Adhesion to Fibronectin (CAM-DR) Influences Acquired Mitoxantrone Resistance in U937 CellsPMID 16489039Read ↗

Reduction in drug-induced DNA double-strand breaks associated with β1 integrin–mediated adhesion correlates with drug resistance in U937 cellsSemantic proximity Read ↗

Selection for Drug Resistance Results in Resistance to Fas-Mediated ApoptosisSemantic proximity Read ↗

Reversal by Hyaluronidase of Adhesion-Dependent Multicellular Drug Resistance in Mammary Carcinoma CellsSemantic proximity Read ↗

Elevation of alpha2(I) collagen, a suppressor of Ras transformation, is required for stable phenotypic reversion by farnesyltransferase inhibitors.Semantic proximity Read ↗

Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase.Semantic proximity Read ↗

Selection of tumor cell variants for resistance to tumor necrosis factor also induces a form of pleiotropic drug resistance.Semantic proximity Read ↗

Nalidixic acid-resistant V79 cells with reduced DNA topoisomerase II activity and amplification prone phenotype.Semantic proximity Read ↗

Integrins regulate the apoptotic response to DNA damage through modulation of p53.Semantic proximity Read ↗

Altered adhesion properties and alpha v integrin expression in a cisplatin‐resistant human ovarian carcinoma cell lineSemantic proximity Read ↗

Peripheral blood lymphocyte binding to a soluble FITC-fibronectin conjugate.Semantic proximity Read ↗

Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.