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Article

Reversal by Hyaluronidase of Adhesion-Dependent Multicellular Drug Resistance in Mammary Carcinoma Cells

18 Sept 1996

Abstract excerpt

BACKGROUND: De novo or acquired resistance to chemotherapeutic drugs continues to be one of the most important obstacles hindering the successful treatment of cancer patients. Consequently, enhancing the efficacy of conventional chemotherapeutic drugs has become an important research goal. Our previous studies using the mouse EMT-6 mammary carcinoma selected for resistance to various alkylating agents in vivo...

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PMID: 8797768
DOI: 10.1093/jnci/88.18.1285

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Source receipt: pubmed, retrieved 7 Sept 2026.

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