LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain

Abstract excerpt

The leucine-rich repeat kinase 2 (LRRK2) gene was recently found to have multiple mutations that are causative for autosomal dominant inherited Parkinson's disease (PD). Previously, we used Northern blot analysis to show that this gene was expressed in the cerebellum, cerebral cortex, medulla, spinal cord, occipital pole, frontal lobe, temporal lobe and caudate putamen. However, a more comprehensive map of LRRK2...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neurological diseases and metabolism
• Share to Neurological disorders and treatments
• Share to Parkinson's Disease Mechanisms and Treatments