Article
Rapid site-specific DNA inversion in Escherichia coli mutants lacking the histonelike protein H-NS.
Journal of bacteriology - 1 Jul 1991
Kawula T H, Orndorff P E
Abstract excerpt
Escherichia coli pilG mutants are thought to have a dramatically higher DNA inversion rate as measured by the site-specific DNA inversion of the type 1 pili pilA promoter. DNA sequence of the pilG gene confirmed its identity to the gene encoding the bacterial histonelike protein H-NS. Unlike other histonelike protein complexes that enhance site-specific DNA recombination, the H-NS protein inhibited this process....
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