Phenotypic analysis of random hns mutations differentiate DNA-binding activity from properties of fimA promoter inversion modulation and bacterial motility.

Abstract excerpt

H-NS is a major Escherichia coli nucleoid-associated protein involved in bacterial DNA condensation and global modulation of gene expression. This protein exists in cells as at least two different isoforms separable by isoelectric focusing. Among other phenotypes, mutations in hns result in const...

Topics

• Bacterial Proteins
• Chromosome Inversion
• Codon, Terminator
• DNA-Binding Proteins
• Escherichia coli
• Fimbriae Proteins
• Frameshift Mutation
• Gene Expression Regulation, Bacterial
• Movement
• Mutagenesis, Site-Directed
• Operon
• Phenotype
• Pili, Sex
• Point Mutation
• Promoter Regions, Genetic
• Recombinant Proteins