Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence.

Molecular and cellular biology - 1 Mar 2006

Binda Olivier, Roy Jean-Sébastien, Branton Philip E

Abstract excerpt

The retinoblastoma binding protein 1 (RBP1) appears to be an important factor in the repression of E2F-dependent transcription by the retinoblastoma protein (pRB) family. The recent identification of the breast carcinoma associated antigen (BCAA) as an RBP1-like protein led us to investigate its biological properties and compare them to RBP1. Like RBP1, BCAA contains a carboxy-terminal R2 domain that elicits...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CHO Cells

Share to Cricetinae

Share to Cricetulus

Share to Histone Deacetylases

Share to Retinoblastoma-Binding Protein 1

Share to SUMO-1 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 16479010
DOI: 10.1128/MCB.26.5.1917-1931.2006
PMCID: PMC1430237

Genes

RBP1
SAP30

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence.PMID 16479010Read ↗

The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature SenescenceSemantic proximity Read ↗

RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.Semantic proximity Read ↗

RB1: a prototype tumor suppressor and an enigma.Semantic proximity Read ↗

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinerySemantic proximity Read ↗

SUMO modification of Stra13 is required for repression of cyclin D1 expression and cellular growth arrest.Semantic proximity Read ↗

Post-translational modifications on the retinoblastoma proteinSemantic proximity Read ↗

Retinoblastoma Protein Paralogs and Tumor SuppressionSemantic proximity Read ↗

Role of the Retinoblastoma Protein in Differentiation and SenescenceSemantic proximity Read ↗

Conserved RB functions in development and tumor suppressionSemantic proximity Read ↗

Acetylation control of the retinoblastoma tumour-suppressor protein.Semantic proximity Read ↗

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth.Semantic proximity Read ↗

Evolving intricacies and implications of E2F1 regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.