Article
Acetylation control of the retinoblastoma tumour-suppressor protein.
Nature cell biology - 1 Jul 2001
Chan H M, Krstic-Demonacos M, Smith L, Demonacos C, La Thangue N B
Abstract excerpt
The retinoblastoma tumour-suppressor protein (pRb) and p300/CBP co-activator proteins are important for control of proliferation and in tumour cells these are sequestered by viral oncoproteins such as E1A. pRb is involved in negatively regulating growth, and p300/CBP proteins have histone acetylt...
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