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Article

CYP2C8 polymorphism among the Portuguese.

Clinical chemistry and laboratory medicine - 1 Jan 2006

Cavaco Isa, Piedade Rita, Gil J Pedro, Ribeiro Vera

Abstract excerpt

Cytochrome P450 2C8 (CYP2C8) is a polymorphic phase I drug-metabolising enzyme involved in the metabolism of a wide variety of xenobiotics, as well as a proposed player in the regulation of vascular tone. Polymorphisms in this gene may have an impact on the metabolism of therapeutic drugs such as paclitaxel and verapamil. In this report we have determined the frequencies of the main non-synonymous CYP2C8 alleles,...

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Source

Identifiers

PMID: 16475901
DOI: 10.1515/CCLM.2006.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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