Article
Type I and type III collagen-platelet interaction: inhibition by type specific receptor peptides.
Thrombosis research - 1 Jan 2007
Zhu Jiaqian, Cole Flecia, Woo-Rasberry Virginia, Fang Xiao Rong, Chiang Thomas M
Abstract excerpt
We have previously cloned and characterized a platelet receptor for type III collagen (47 kDa) from a human bone marrow cDNA phage library and defined two active peptides. We also cloned and characterized a platelet receptor for type I collagen (65 kDa) and defined an active peptide. Our objective was to study whether there is type specificity of these active peptides. We have engineered a mutant receptor clone...
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