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Development of a software for kinship analysis considering linkage and mutation based on a Bayesian network.

Forensic science international. Genetics - 1 Jul 2020

Morimoto Chie, Tsujii Hideaki, Manabe Sho, Fujimoto Shuntaro, Hirai Eriko, Hamano Yuya, Tamaki Keiji

Abstract excerpt

In forensic DNA testing, the number of tested short tandem repeat loci has increased owing to new multiplex kits with additional loci. Although this advancement provides improved discrimination power, the effects of linkage and mutation must be considered during kinship analysis. However, no software currently includes both of these effects. In this study, we developed new freeware called KinBN for kinship...

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PMID: 32289730
DOI: 10.1016/j.fsigen.2020.102279

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