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Article

The tail of a yeast class V myosin, myo2p, functions as a localization domain.

Molecular biology of the cell - 1 Apr 1999

Reck-Peterson S L, Novick P J, Mooseker M S

Abstract excerpt

Myo2p is a yeast class V myosin that functions in membrane trafficking. To investigate the function of the carboxyl-terminal-tail domain of Myo2p, we have overexpressed this domain behind the regulatable GAL1 promoter (MYO2DN). Overexpression of the tail domain of Myo2p results in a dominant-negative phenotype that is phenotypically similar to a temperature-sensitive allele of myo2, myo2-66. The tail domain of...

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Identifiers

PMID: 10198053
DOI: 10.1091/mbc.10.4.1001
PMCID: PMC25227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The tail of a yeast class V myosin, myo2p, functions as a localization domain.PMID 10198053Read ↗

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Head-to-tail regulation is critical for the in vivo function of myosin V.Semantic proximity Read ↗

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