Article
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres.
Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 2006
Feldser David, Strong Margaret A, Greider Carol W
Abstract excerpt
Telomerase-mediated telomere addition counteracts telomere shortening due to incomplete DNA replication. Short telomeres are the preferred substrate for telomere addition by telomerase; however, the mechanism by which telomerase recognizes short telomeres is unclear. In yeast, the Ataxia telangiectasia mutated (Atm) homolog, Tel1, is necessary for normal telomere length regulation likely by altering telomere...
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