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Article

Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.

The Journal of clinical endocrinology and metabolism - 1 May 2006

Redondo Maria J, Babu Sunanda, Zeidler Adina, Orban Tihamer, Yu Liping, Greenbaum Carla, Palmer Jerry P, Cuthbertson David, Eisenbarth George S, Krischer Jeffrey P, Schatz Desmond

Abstract excerpt

CONTEXT: Human leukocyte antigen (HLA) DQ haplotypes have the strongest genetic association with type 1 diabetes (T1DM) risk. OBJECTIVE: The objective of the study was to analyze whether HLA DQ alleles influence the development of antiislet autoantibodies, the progression to T1DM among autoantibody-positive relatives, or both. DESIGN: The Diabetes Prevention Trial-1 screened more than 90,000 nondiabetic relatives...

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Identifiers

PMID: 16464953
DOI: 10.1210/jc.2005-1695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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