Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of anti-tumor immunity specific to murine glioma by vaccination with tumor cell lysate-pulsed dendritic cells engineered to produce interleukin-12.

Cancer immunology, immunotherapy : CII - 1 Nov 2006

Kim Chang-Hyun, Hong Min-Jung, Park Sung-Dong, Kim Choong-Kwon, Park Mi-Young, Sohn Hyun-Jung, Cho Hyun-Il, Kim Tai-Gyu, Hong Yong-Kil

Abstract excerpt

AIM: The aim of this study was to develop an immunotherapy specific to a malignant glioma by examining the efficacy of glioma tumor-specific cytotoxic T lymphocytes (CTL) as well as the anti-tumor immunity by vaccination with dendritic cells (DC) engineered to express murine IL-12 using adenovirus-mediated gene transfer and pulsed with a GL26 glioma cell lysate (AdVIL-12/DC+GL26) was investigated. EXPERIMENT1:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Vaccines

Share to Dendritic Cells

Share to Glioma

Share to Interleukin-12

Share to Protein Engineering

Share to Spleen

Source

Open in PubMed Open full text

Identifiers

PMID: 16463038
DOI: 10.1007/s00262-006-0134-x
PMCID: PMC11029860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of anti-tumor immunity specific to murine glioma by vaccination with tumor cell lysate-pulsed dendritic cells engineered to produce interleukin-12.PMID 16463038Read ↗

Dendritic Cell Vaccination in Conjunction with a TLR Agonist Polarizes Interferon Immune Responses in Malignant Glioma PatientsSemantic proximity Read ↗

Gene therapy of malignant gliomas: a pilot study of vaccination with irradiated autologous glioma and dendritic cells admixed with IL-4 transduced fibroblasts to elicit an immune response.Semantic proximity Read ↗

Superior protective and therapeutic effects of IL-12 and IL-18 gene-transduced dendritic neuroblastoma fusion cells on liver metastasis of murine neuroblastoma.Semantic proximity Read ↗

Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma.Semantic proximity Read ↗

Intratumoral gene delivery of 4-1BBL boosts IL-12-triggered anti-glioblastoma immunitySemantic proximity Read ↗

Human autologous in vitro models of glioma immunogene therapy using B7-2, GM-CSF, and IL12.Semantic proximity Read ↗

Self-adjuvant nanovaccine delivering cytokines as a novel platform to empower glioblastoma immunotherapySemantic proximity Read ↗

CD40ligand-expressing dendritic cells induce regression of hepatocellular carcinoma by activating innate and acquired immunity in vivo.Semantic proximity Read ↗

HSP70L1-mediated intracellular priming of dendritic cell vaccination induces more potent CTL response against cancer.Semantic proximity Read ↗

Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.Semantic proximity Read ↗

Suppression of murine tumour growth through CD8+ cytotoxic T lymphocytes via activated DEC-205+ dendritic cells by sequential administration of α-galactosylceramide in vivo.Semantic proximity Read ↗

A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.