Article
Increased risk of adefovir resistance in patients with lamivudine-resistant chronic hepatitis B after 48 weeks of adefovir dipivoxil monotherapy.
Hepatology (Baltimore, Md.) - 1 Jun 2006
Lee Yoon-Seon, Suh Dong Jin, Lim Young-Suk, Jung Suk Won, Kim Kang Mo, Lee Han Chu, Chung Young-Hwa, Lee Yung Sang, Yoo Wangdon, Kim Soo-Ok
Abstract excerpt
Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance in treatment-naïve chronic hepatitis B patients, the association of ADV resistance with previous lamivudine (LAM) resistance is not well understood. We compared the emergence of the ADV-resistant mutations...
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