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Article

Genetic characterization of the APC locus involved in familial adenomatous polyposis.

Gastroenterology - 1 Jul 1991

Olschwang S, Weiffenbach B, Laurent-Puig P, Melot T, Vassal A, Falls K, Salmon R J, Parc R, Strong L, Nakamura Y

Abstract excerpt

Familial adenomatous polyposis is a rare disease inherited in a Mendelian dominant fashion. It is characterized by the occurrence of more than 100 adenomatous polyps in the large bowels of affected individuals. The genetic defect responsible for adenomatous polyposis resides at a locus called APC which has been localized to the long arm of human chromosome 5. In this study, the APC locus was mapped with respect...

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Identifiers

PMID: 1646139
DOI: 10.1016/0016-5085(91)90472-w

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Genetic characterization of the APC locus involved in familial adenomatous polyposis.PMID 1646139Read ↗

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