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Article

Attenuated familial adenomatous polyposis in a man with an interstitial deletion of chromosome arm 5q

8 Oct 1999

Abstract excerpt

Familial adenomatous polyposis (FAP) is an inherited colon cancer syndrome caused by mutations in the APC gene on chromosome region 5q21. Patients typically present with several hundred to several thousand polyps throughout the colon. Benign and malignant extracolonic manifestations are often present. Attenuated FAP (AFAP) is a recognized variant of FAP in which patients present with fewer than 100 polyps and...

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Identifiers

PMID: 10494086
DOI: 10.1002/(sici)1096-8628(19991008)86:4<321::aid-ajmg4>3.0.co;2-0

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Source receipt: pubmed, retrieved 7 Sept 2026.

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