Article
The myb-related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers.
Cell death and differentiation - 1 Oct 2006
Brun S, Rincheval-Arnold A, Colin J, Risler Y, Mignotte B, Guénal I
Abstract excerpt
We carried out gain-of-function mutagenesis screening and identified a mutant in which GAL4 induction led to both hyperplasia and apoptosis. The gene involved was identified as stonewall (stwl), a myb-related gene involved in germ cell proliferation and differentiation during oogenesis. As observed with dmyb, the ectopic expression of stwl(UY823) inhibited endoreplication in salivary glands. We also found that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.