Article
klumpfuss regulates cell death in the Drosophila retina.
Mechanisms of development - 1 Jun 2004
Rusconi Jamie C, Fink Jill L, Cagan Ross
Abstract excerpt
Programmed cell death (PCD) plays a central role in the sculpting and maturation of developing epithelia. In adult tissue, PCD plays a further role in the prevention of malignancy though removal of damaged cells. Here, we report that mutations in klumpfuss result in an excess of support cells during maturation of the developing Drosophila pupal retina. These ectopic cells are the result of a partial and specific...
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