Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease.

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Article

Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease.

Sleep - 1 Jan 2006

Rissling Ida, Frauscher Birgit, Kronenberg Florian, Tafti Mehdi, Stiasny-Kolster Karin, Robyr Anne-Catherine, Körner Yvonne, Oertel Wolfgang Hermann, Poewe Werner, Högl Birgit, Möller Jens Carsten

Abstract excerpt

STUDY OBJECTIVE: A preliminary study by our group suggested an association between daytime sleepiness and the catechol-O-methyltransferase (COMT) val158met polymorphism (rs4680) in patients with Parkinson disease (PD). We sought to confirm this association in a large group of patients with PD. DESIGN: Genetic association study in patients with PD. SETTING: Movement disorder sections at 2 university hospitals....

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Identifiers

PMID: 16453988

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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