Article
Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival.
Infection and immunity - 1 Feb 2003
Gao Lian-Yong, Groger Richard, Cox Jeffery S, Beverley Stephen M, Lawson Elise H, Brown Eric J
Abstract excerpt
Pathogenic mycobacteria survive and replicate within host macrophages, but the molecular mechanisms involved in this necessary step in the pathogenesis of infection are not completely understood. Mycobacterium marinum has recently been used as a model for aspects of the pathogenesis of tuberculosis because of its close genetic relationship to Mycobacterium tuberculosis and because of similarities in the pathology...
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