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Article

Including endophenotypes as covariates in variance component heritability and linkage analysis.

BMC genetics - 30 Dec 2005

Bailey Julia N

Abstract excerpt

The purpose of these analyses was to determine if incorporating or adjusting for covariates in genetic analyses helped or hindered in genetic analyses, specifically heritability and linkage analyses. To study this question, two types of covariate models were used in the simulated Genetic Analysis Workshop 14 dataset in which the true gene locations are known. All four populations of one replicate were combined...

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PMID: 16451660
DOI: 10.1186/1471-2156-6-S1-S49
PMCID: PMC1866735

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