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Article

Covariate linkage analysis of GAW14 simulated data incorporating subclinical phenotype, sex, population, parent-of-origin, and interaction.

BMC genetics - 30 Dec 2005

Hamshere Marian L, MacGregor Stuart, Moskvina Valentina, Nikolov Ivan N, Holmans Peter A

Abstract excerpt

BACKGROUND: We evaluate a method for the incorporation of covariates into linkage analysis using the Genetic Analysis Workshop 14 simulated data. Focusing on a randomly chosen replicate (42) we investigated the effect of the 12 subclinical phenotypes, sex, population, and parent-of-origin on the linkage signal from a model-free linkage analysis of Kofendrerd Personality Disorder. RESULTS: We detected a linkage...

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Identifiers

PMID: 16451656
DOI: 10.1186/1471-2156-6-S1-S45
PMCID: PMC1866739

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