Article
Linkage analysis of alcohol dependence using MOD scores.
BMC genetics - 30 Dec 2005
Strauch Konstantin, Fürst Robert, Rüschendorf Franz, Windemuth Christine, Dietter Johannes, Flaquer Antonia, Baur Max P, Wienker Thomas F
Abstract excerpt
Alcohol dependence is a typical example of a complex trait that is governed by several genes and for which the mode of inheritance is unknown. We analyzed the microsatellite markers and the Affymetrix single-nucleotide polymorphisms (SNPs) for a subset of the Collaborative Study on the Genetics of Alcoholism family sample, 93 pedigrees of Caucasian ancestry comprising 919 persons, 390 of whom are affected...
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