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Article

Testing association in the presence of linkage--a powerful score for binary traits.

Genetic epidemiology - 1 Sept 2007

Jonasdottir Gudrun, Humphreys Keith, Palmgren Juni

Abstract excerpt

We present a score for testing association in the presence of linkage for binary traits. The score is robust to varying degrees of linkage, and it is valid under any ascertainment scheme based on trait values as well as under population stratification. The score test is derived from a mixed effects model where population level association is modeled using a fixed effect and where correlation among related...

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PMID: 17436308
DOI: 10.1002/gepi.20226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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